Reporting Problems with Flea and Tick Spot on Products

Keep the product package after use in case side effects
occur. You will want to have the instructions available,
as well as contact information for the manufacturer.

•To report problems with spot-on flea or tick products,
contact the National Pesticide Information Center (NPIC)

•To report problems with FDA approved flea or tick drug
products, contact the drug manufacturer directly (see
contact information on product labeling) or report to
FDA's Center for Veterinary Medicine on a Form FDA
1932a. Merial's phone number is


•If your pet needs immediate medical care, call your
local veterinarian, a local animal emergency clinic,
or the National Animal Poison Control Center at

The NAPCC charges a fee for consultation.


If you go to this site, you will see all the complaints the
EPA has gotten on Merial products with Fipronil to April
2018.  You will need to be able to open pdf files.
Go to the right side of the page and click search FIOA
requests. In search box put in number
EPA-HQ-2018-005237. Uncheck all agencies if it is
checked. Then highlight the Environmental Protection
Agency in the box. Then click search. A yellow
highlighted tracking number will appear. Click on the
number and then download all. Must have Adobe Acrobat
Reader to open. Two files will download on your
Click on them to open. On the last page of each report is
the codes used to identify what happened to pets after
using Frontline products.

Page 4

2010      WASHINGTON – Due to a significant increase in adverse incidents, the U.S.
Environmental Protection Agency is taking a series of actions to increase the safety of spot-
on pesticide products for flea and tick control for cats and dogs. Immediately, EPA will
begin reviewing labels to determine which ones need stronger and clearer labeling
statements. Next, EPA will develop more stringent testing and evaluation requirements for
both existing and new products. EPA expects these steps will help prevent adverse
reactions. In dogs and cats that can include skin effects, such as irritation, redness, or
gastrointestinal problems that include vomiting or diarrhea, or effects to the nervous
system, such as trembling, appearing depressed or seizures—from pet spot-on products.

“EPA is committed to better protecting the health and safety of pets and families in all your
pet to a pesticide.”

Following the 2008 increase in incident reports, EPA received additional information from
the pet spot-on pesticide registrants and others and began an intensive evaluation of these
products. Today, EPA is reporting the results of this evaluation, and taking steps to
address the spike in reported incidents.  

Among immediate actions that EPA will pursue are: (in 2010)

· Requiring manufacturers of spot-on pesticide products to improve labeling, making
instructions clearer to prevent product misuse.  

· Requiring more precise label instructions to ensure proper dosage per pet weight.  

· Requiring clear markings to differentiate between dog and cat products, and disallowing
similar brand names for dog and cat products. Similar names may have led to misuse.  

· Requiring additional changes for specific products, as needed, based on product-specific

When new products are registered, granting only conditional, time-limited registrations to
allow for post-marketing product surveillance. If there are incidents of concern associated
with the product, EPA will take appropriate regulatory action.  

Restricting the use of certain inert ingredients that EPA finds may contribute to the
The EPA doesn't realize that we do put the right amount of FP on our pets and
follow the directions. They don't realize this is a poison and as long as it's on the
market, there will be problems with our pets who had it applied to them. But then
again maybe they realize it and choose not to do anything about it.

It is now 2019 (9 years later) and NOTHING has been done since. Frontline
Plus is still killing our pets and making them have serious side effects. We
think it's about time they do their job and protect our pets by taking this
poison off the market.

Jennifer's Story
Unfortunately I had no idea how poisonous all that topical stuff is. My  poodle started to have
seizures 48 hrs after I put Frontline on.  I took her to the vet, who of course denied that it could
possibly be from Frontline. She had seizures ever since, but lately much less in frequency. I was
told that it takes a year to get totally out of their system. My vet stopped selling Frontline. Does
that tell us anything?

Wendy's  Story
Most of our Vets that sell Frontline will not agree that there is a problem. Why I do not know, as
they are not libel for what they sell, only the makers of Frontline is. Personally I am sick and tired
of seeing my poor dog going through so much pain, almost totally blind now, shots twice a day,
and so brave. I can not even move my furniture around so he does not hurt himself running into
anything. He is like a child, cries so and bruises himself.  I worry so he may even break a bone
from the Diabetic shots.  Yes Frontline must stop hurting our animals that we spend good money
on just to protect our friends from ticks and fleas.  Please  join this fight. You may just save a life.

Thomas's Story
I have used Fontline Plus for dogs during the past five years and seemingly without problems
until about 15 months ago. I noticed that our six year old Border Collie began having problems
with her rear legs. We thought she must be suffering from arthritis or some kind of degenerative
hip problems. It became very difficult for her to get up from a prone position, difficult for her to
squat to pee, impossible for her to jump up onto the bed, and when she sits her left hip now tucks
under her. The symptoms got worse for about 3 months so about 12 months ago, I took her to the
vet for xrays and diagnosis. Two different vets evaluated her and said they saw no sign of hip
displacement and not visible problem with arthritis showed on the xrays. They suggested we treat
her for arthritis for 60 days and see if she improved. She did not get improvement from that
medication. Around that time I read an article about side effects in some dogs from Frontline so in
desperation I discontinued use of frontline on her last May. Happily she showed slow but steady
improvement from May until December. She is about 80% recovered. I cannot say absolutely a
casual relationship between the discontinued use of Frontline Plus and her recovery but it is the
only change we made. It is enough to make me believe this was a reaction to the Fontline
medication for her.
There IS a report by David Wallnga M.D and Linda Greer PHD regarding the side
effects of flea and tick preventatives
It's very interesting as it tells of the effects these poisons have on pets, children
and pet owners along with persons who work in vets offices and take care of our
pets like groomers. You may have to have a way to open PDF files like Adobe.   
Here is the link in case you want to read it: